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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK13
All Species:
11.21
Human Site:
S433
Identified Species:
27.41
UniProt:
Q14004
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14004
NP_003709.3
1512
164923
S433
H
R
L
S
R
S
R
S
R
H
S
S
I
S
P
Chimpanzee
Pan troglodytes
XP_001139939
1512
164915
S433
H
R
L
S
R
S
R
S
R
H
S
S
I
S
P
Rhesus Macaque
Macaca mulatta
XP_001088594
1490
164086
V425
K
E
S
K
G
S
P
V
F
L
P
R
K
E
N
Dog
Lupus familis
XP_533082
1377
150158
T386
K
D
V
K
K
L
K
T
E
H
A
P
S
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZA1
1511
164590
S434
H
R
L
S
R
S
R
S
R
H
S
S
I
S
P
Rat
Rattus norvegicus
Q3MJK5
1484
163772
A408
K
K
K
E
R
A
A
A
A
A
A
A
K
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425866
1032
115177
Y70
V
I
K
P
L
V
E
Y
D
D
I
S
S
D
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687417
1286
141523
R324
S
P
Y
G
Q
R
R
R
S
R
S
P
T
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46551
730
82410
Sea Urchin
Strong. purpuratus
XP_789337
1264
139419
K299
A
A
K
A
K
V
V
K
Q
E
K
E
P
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
41.4
82.5
N.A.
95.1
41.6
N.A.
N.A.
29.7
N.A.
44
N.A.
N.A.
N.A.
24.6
32.6
Protein Similarity:
100
99.8
53.5
84.5
N.A.
96.8
53.9
N.A.
N.A.
37.9
N.A.
55
N.A.
N.A.
N.A.
33.3
46.9
P-Site Identity:
100
100
6.6
6.6
N.A.
100
6.6
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
6.6
40
N.A.
100
40
N.A.
N.A.
6.6
N.A.
20
N.A.
N.A.
N.A.
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
0
10
10
10
10
10
20
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
10
10
0
0
0
10
20
% D
% Glu:
0
10
0
10
0
0
10
0
10
10
0
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
30
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
10
0
30
0
0
% I
% Lys:
30
10
30
20
20
0
10
10
0
0
10
0
20
0
0
% K
% Leu:
0
0
30
0
10
10
0
0
0
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
10
0
10
0
0
10
0
0
0
10
20
10
20
40
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
30
0
0
40
10
40
10
30
10
0
10
0
0
0
% R
% Ser:
10
0
10
30
0
40
0
30
10
0
40
40
20
40
20
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% T
% Val:
10
0
10
0
0
20
10
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _